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automated peptide synthesizer aapptec focus xc  (AAPPTec Inc)

 
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    Structured Review

    AAPPTec Inc automated peptide synthesizer aapptec focus xc
    Automated Peptide Synthesizer Aapptec Focus Xc, supplied by AAPPTec Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/automated+peptide+synthesizer+aapptec+focus+xc/automated+peptide+synthesizer+aapptec+focus+xc/pmc11700610-38-20-19
    Average 90 stars, based on 1 article reviews
    automated peptide synthesizer aapptec focus xc - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Construct:

    Article Title: Total synthesis of μ-conotoxin lt5d
    Article Snippet: .. Automated synthesis of precursor linear peptides was accomplished with an automated peptide synthesizer (Aapptec Focus XC) using standard solid-phase synthesis protocols and Fmocprotection strategy as previously described by Amblard et al. with modifications.1 Briefly, linear peptides were constructed on 2-chlorotrityl chloride resin on a 140 μmol scale per batch using 5fold excess of amino acids. ..

    Article Title: Total synthesis of μ-conotoxin lt5d
    Article Snippet: .. Automated synthesis of precursor linear peptides was accomplished with an automated peptide synthesizer (Aapptec Focus XC) using standard solid-phase synthesis protocols and Fmocprotection strategy as previously described by Amblard et al. with modifications.1 Briefly, linear peptides were constructed on 2-chlorotrityl chloride resin on a 140 μmol scale per batch using 5- fold excess of amino acids. ..

    other:

    Article Title: Thrombopoietic agents enhance bone healing in mice, rats, and pigs
    Article Snippet: Thereafter, the following peptide sequence was added onto the peptide using the solid phase procedures listed above using the AAPPTEC FOCUS XC automated peptide synthesizer: Ile-Glu-Gly-Pro-Thr-Leu-Arg-Gln-Npa-Leu-Ala-Ala-Arg-Sar.

    Article Title: The Meta-Position of Phe4 in Leu-Enkephalin Regulates Potency, Selectivity, Functional Activity, and Signaling Bias at the Delta and Mu Opioid Receptors
    Article Snippet: Peptides were synthesized using an Aapptec Focus XC automated peptide synthesizer coupled with a heating system using a solid phase peptide synthesis protocol using Fmoc chemistry.

    Synthesized:

    Article Title: Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.
    Article Snippet: We report the discovery of sulanemadlin (ALRN6924), the first cell-permeating, stabilized α-helical peptide to enter clinical trials.. ALRN-6924 is a “stapled peptide” that mimics the Nterminal domain of the p53 tumor suppressor protein.. It binds with high affinity to both MDM2 and MDMX (also known as MDM4), the endogenous inhibitors of p53, to activate p53 signaling in cells having a non-mutant, or wild-type TP53 genotype (TP53-WT).

    Isolation:

    Article Title: Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.
    Article Snippet: We report the discovery of sulanemadlin (ALRN6924), the first cell-permeating, stabilized α-helical peptide to enter clinical trials.. ALRN-6924 is a “stapled peptide” that mimics the Nterminal domain of the p53 tumor suppressor protein.. It binds with high affinity to both MDM2 and MDMX (also known as MDM4), the endogenous inhibitors of p53, to activate p53 signaling in cells having a non-mutant, or wild-type TP53 genotype (TP53-WT).

    High Performance Liquid Chromatography:

    Article Title: Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.
    Article Snippet: We report the discovery of sulanemadlin (ALRN6924), the first cell-permeating, stabilized α-helical peptide to enter clinical trials.. ALRN-6924 is a “stapled peptide” that mimics the Nterminal domain of the p53 tumor suppressor protein.. It binds with high affinity to both MDM2 and MDMX (also known as MDM4), the endogenous inhibitors of p53, to activate p53 signaling in cells having a non-mutant, or wild-type TP53 genotype (TP53-WT).



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